Product Name: Generic Priligy
Active Ingredients: Dapoxetine
Price: $0.95 per pill
Generic Priligy is a drug applied for the prevention of premature ejaculation. Its main component is dapoxetine. Its dosage is 100 mg. It provides the effect for several hours. Better not to mix with alcohol beverages and other meds for ED and PE.
Generic Priligy is a drug for premature ejaculation treatment. It contains dapoxetine. The mechanism of its action during premature ejaculation is associated with inhibition of serotonin reuptake by neurons, followed by increased action of the neurotransmitter on pre- and postsynaptic receptors. The ejaculation mechanism is mainly regulated by the sympathetic nervous system. Dapoxetine affects the ejaculation reflex, increasing the latent period and reducing the duration of the motor neurons’ reflex impulse of the perineal ganglia.
Priligy is prescribed for the treatment of premature ejaculation in men aged 18 to 64 years old.
How to take this medicine?
Oral administration. The tablet should be swallowed whole, washed down with at least one full glass of water. Priligy can be taken irregardless of meals.
Adult males 18 to 64 years old
The recommended starting dose of Priligy for all men is 30 mg; this dose is taken 1-3 hours before the intended sexual intercourse. With an insufficient effect and good tolerance, it can be increased to 60 mg. The maximum recommended frequency is 1 time in 24 hours.
The doctor prescribing Priligy for the treatment of premature ejaculation should assess the risk and benefit of using the drug after the first 4 weeks of treatment or after taking 6 doses and must determine the risk-benefit ratio to decide on the advisability of further treatment with Priligy.
- Hypersensitivity to dapoxetine hydrochloride or any auxiliary component of the drug;
- Severe heart disease in the absence of a constant pacemaker, severe coronary heart disease or valvular lesions);
- Moderate and severe violations of liver function;
- Severe renal impairment;
- Children and adolescents under the age of 18;
- Lactose intolerance.
- Mental disorders: often – anxiety, agitation, anxiety, insomnia, unusual dreams, decreased libido; infrequently – depression, depressed mood, euphoric mood, mood swings, increased excitability, indifference, apathy, confusion, disorientation, impaired thinking, excessive alertness, sleep disturbance, intrasomnic disorders, nightmares, bruxism, loss of libido, anorgasmia.
- The nervous system: very often – headache, dizziness; often – drowsiness, impaired attention, tremor, paresthesia; infrequently – fainting, vasovagal fainting, postural dizziness, akathasia, dysgeusia, hypersomnia, lethargy, sedation, decreased consciousness; rarely – dizziness during physical exertion, sudden falling asleep.
- The organ of vision: often – blurred vision; infrequently – mydriasis, eye pain, visual impairment.
- The organ of hearing and balance conditions: often – ringing in the ears; infrequently – vertigo.
- The cardiovascular system: infrequently – blockade of the sinoatrial node, sinus bradycardia, tachycardia; often – tides; infrequently – hypotension, systolic hypertension.
- The respiratory tract, chest and mediastinal organs: often – swelling of the sinuses, yawning.
- The digestive system: very often – nausea; often – diarrhea, vomiting, constipation, abdominal pain, epigastric pain, dyspeptic symptoms, flatulence, discomfort in the stomach, bloating, dry mouth; rarely – urinary urgency.
- The skin and subcutaneous tissue: often – excessive sweating; infrequently – itching, cold sweat.
- The reproductive system and mammary glands: often – erectile dysfunction; infrequently – insufficiency of ejaculation, violation of male orgasm, male genital paresthesia.
- General disorders: often – fatigue, irritability; infrequently – weakness, a feeling of heat, a feeling of anxiety, unusual sensations, a feeling of intoxication.
- Simultaneous administration of MAO inhibitors and administration within 14 days after their use withdrawal. MAO inhibitors should not be taken within 7 days after Priligy discontinuation;
- Concomitant use of thioridazine with dapoxetine is prohibited. Dapoxetine can be taken within 14 days after its withdrawal. Similarly, thioridazine can not be taken within 7 days after stopping PE therapy;
- Concomitant use of serotonin reuptake inhibitors (SSRI selective selective serotonin reuptake inhibitors), serotonin and norepinephrine reuptake inhibitors and tricyclic antidepressants) and other drugs that have serotonergic effects (for example, L-tryptophan, tryptanium, linrazole, tramazolide is prohibited. The therapy can be started within 14 days after these drugs’ discontinuation;
- Simultaneous administration with active CYP3A4 inhibitors, for example, ketoconazole, itraconazole, ritonavir, saquinavir, telithromycin, nefazodone, nelfinavir, atazanavir, etc.