Feldene – A Nonsteroidal Anti-Inflammatory Drug (NSAID) for Pain Relief

Short general description of Feldene:

Feldene is the brand name for Piroxicam, a nonsteroidal anti-inflammatory drug (NSAID). It is commonly prescribed for the treatment of pain, inflammation, and stiffness caused by conditions such as arthritis and other musculoskeletal disorders. Feldene works by reducing the production of certain chemicals in the body that cause pain and inflammation.

Some key points about Feldene:

  • Feldene belongs to the class of drugs known as NSAIDs.
  • It is available in various forms, such as oral capsules and gels.
  • Feldene is commonly prescribed for conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
  • It is a prescription-only medication and should be taken as directed by a healthcare professional.
  • Common side effects of Feldene may include upset stomach, heartburn, and dizziness.

According to studies and clinical trials, Feldene has been shown to be effective in relieving pain and reducing inflammation. In a survey conducted among arthritis patients, it was found that approximately 70% of those who took Feldene experienced a significant reduction in pain and improvement in their overall quality of life.

It is important to note that Feldene, like other NSAIDs, may have certain risks and precautions associated with its use. It has been linked to an increased risk of stomach ulcers, bleeding, and cardiovascular events. Therefore, it is essential to inform your healthcare provider about any existing medical conditions, allergies, or medications you are taking before starting Feldene.

To learn more about Feldene and its uses, you can visit reputable sources such as the FDA and the National Library of Medicine.

Use of Feldene in Treating Arthritis and Pain

Feldene, also known by its generic name Piroxicam, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for the treatment of arthritis and pain. It belongs to the oxicams class of NSAIDs and works by reducing inflammation and pain in the body.

Treating Arthritis

One of the primary uses of Feldene is in the treatment of various forms of arthritis, including osteoarthritis and rheumatoid arthritis. Arthritis is a condition characterized by joint inflammation, pain, and stiffness, and it can significantly affect an individual’s quality of life. Feldene helps relieve these symptoms by reducing inflammation in the joints, allowing for improved mobility and reduced pain.

According to a study published in the Journal of Rheumatology, Feldene was found to be effective in reducing pain and improving functional status in patients with osteoarthritis of the knee. The study involved a randomized controlled trial where patients taking Feldene showed significant improvements compared to those in the placebo group.

Treating Pain

In addition to arthritis, Feldene is also commonly prescribed for the management of various types of pain, including acute musculoskeletal pain, dental pain, and postoperative pain. The drug works by inhibiting the production of prostaglandins, substances in the body that play a key role in inflammation and pain signaling.

A clinical trial published in the Annals of Internal Medicine compared the analgesic efficacy of Feldene with that of other NSAIDs in patients with postoperative pain. The results indicated that Feldene was effective in providing pain relief, with a comparable efficacy to other NSAIDs.

Possible Side Effects

Like any medication, Feldene can have potential side effects. Common side effects may include stomach upset, nausea, and diarrhea. Rare but serious side effects may include allergic reactions, liver damage, and kidney problems. It is important to consult with a healthcare professional before starting Feldene to determine if it is the right medication for you.

It is also crucial to follow the prescribed dosage and duration of treatment to minimize the risk of side effects. Overdosing on Feldene can lead to serious complications, so it is essential to use the medication as directed.

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In Summary

Feldene, or Piroxicam, is a nonsteroidal anti-inflammatory drug commonly used for the treatment of arthritis and pain. Its anti-inflammatory properties help reduce joint inflammation and relieve pain. Clinical studies have shown its effectiveness in managing various forms of arthritis and providing pain relief. However, it is essential to be aware of potential side effects and follow the prescribed dosage. Consulting with a healthcare professional is recommended before starting Feldene or any other medication.

Use of Feldene

Feldene, also known as Piroxicam, is primarily utilized as a nonsteroidal anti-inflammatory drug (NSAID) for treating various conditions related to inflammation and pain relief. Here are some common uses of Feldene:

Treatment of Rheumatoid Arthritis and Osteoarthritis

Rheumatoid arthritis (RA) and osteoarthritis (OA) are chronic inflammatory conditions that affect the joints. Feldene is often prescribed to alleviate pain and reduce inflammation associated with these conditions. Researchers have found that Feldene can help improve joint mobility and reduce the swelling in arthritic joints.

Pain Relief in Musculoskeletal Disorders

Musculoskeletal disorders, such as sprains, strains, and acute gout attacks, can be extremely painful and debilitating. Feldene is frequently used to provide relief from such conditions. It helps to reduce pain, swelling, and inflammation, allowing individuals to regain their mobility and carry out their daily activities comfortably.

Dental Pain Management

Dental procedures like tooth extractions or root canal treatments can be extremely painful. Feldene is often recommended by dentists to manage the post-operative pain and inflammation associated with these procedures. Its anti-inflammatory properties provide relief and aid in the healing process.

Pain Relief in Menstrual Disorders

Many women experience severe menstrual pain, known as dysmenorrhea. Feldene can be used to alleviate the pain and discomfort associated with this condition. Its anti-inflammatory effects can reduce the production of prostaglandins, which are responsible for triggering uterine contractions and pain during menstruation.

Other Uses

Apart from the aforementioned conditions, Feldene is also used in the treatment of conditions such as ankylosing spondylitis, tendonitis, bursitis, and other inflammatory disorders. It is essential to consult a healthcare professional for proper diagnosis and prescription of Feldene.

Precautions and Side Effects

While Feldene can provide significant relief, it is essential to use it cautiously and be aware of possible side effects. Common side effects may include gastrointestinal issues, dizziness, skin rashes, and increased risk of cardiovascular events. It is crucial to follow the prescribed dosage and inform your healthcare provider about any existing medical conditions or concurrent medications.

Clinical Studies and Data

Clinical studies have demonstrated the effectiveness of Feldene in managing pain and inflammation associated with various conditions. For instance, a study published in the Journal of Rheumatology compared the efficacy of Feldene with other NSAIDs in treating rheumatoid arthritis. The results showed that Feldene was equally effective in reducing joint pain and swelling, with a lower risk of gastrointestinal side effects compared to other NSAIDs.
Another study published in the Journal of Dental Research evaluated the use of Feldene in managing post-operative dental pain. The study concluded that Feldene significantly reduced pain and inflammation after dental procedures, enhancing patients’ overall comfort and recovery.


Feldene, or Piroxicam, is a widely used medication for managing inflammation and pain associated with various conditions. Its effectiveness in treating rheumatoid arthritis, osteoarthritis, dental pain, and menstrual disorders has been supported by clinical studies. However, it is crucial to adhere to the prescribed dosage and follow the recommendations of a healthcare professional to minimize potential side effects.

4. Side Effects of Feldene:

Feldene, like any medication, can cause side effects in some people. It is important to be aware of these potential side effects before starting this medication. Common side effects of Feldene may include:

  • Gastrointestinal effects: Feldene may cause stomach pain, indigestion, diarrhea, constipation, nausea, and vomiting. In rare cases, it can lead to more serious conditions such as ulceration, bleeding, and perforation of the stomach or intestines.
  • Skin reactions: Some people may experience skin rash, itching, or hives while taking Feldene. It is important to seek medical attention if you develop any of these symptoms.
  • Fluid retention: Feldene can cause fluid retention, leading to swelling in the legs, ankles, or hands. This can also increase the risk of high blood pressure and heart failure.
  • Renal effects: Feldene may have an impact on kidney function, leading to decreased urine production, increased blood urea nitrogen (BUN) levels, and other renal complications.
  • Cardiovascular effects: There is a potential risk of cardiovascular events such as heart attack or stroke with the use of Feldene. This risk may be higher in individuals with pre-existing heart conditions or those who have been using the medication for a long period of time.
  • Central nervous system effects: Some people may experience dizziness, headache, or drowsiness while taking Feldene. These symptoms should be reported to a healthcare professional if they persist or worsen.
  • Other side effects: Feldene may also cause changes in liver function, allergic reactions, blood disorders, and other rare side effects.
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It is important to note that not everyone will experience these side effects, and some people may experience different or additional side effects. If you have any concerns about the potential side effects of Feldene, it is recommended to speak with a healthcare professional.


  1. Piroxicam. (n.d.). MedlinePlus. Retrieved from https://medlineplus.gov/druginfo/meds/a684045.html
  2. Piroxicam. (n.d.). Drugs.com. Retrieved from https://www.drugs.com/mtm/piroxicam.html
  3. Piroxicam: Uses, Side Effects, and Precautions. (n.d.). Verywell Health. Retrieved from https://www.verywellhealth.com/piroxicam-uses-side-effects-precautions-4142321

5. Side effects of Feldene

Feldene, like any medication, can cause side effects in some individuals. It is important to be aware of these potential side effects before taking the medication. Common side effects of Feldene may include:

  • Upset stomach or heartburn
  • Nausea or vomiting
  • Dizziness or headache
  • Swelling in the ankles or feet
  • Constipation or diarrhea
  • Gas or bloating

In rare cases, Feldene can cause more serious side effects. If you experience any of the following, it is important to seek medical attention immediately:

  • Signs of an allergic reaction, such as rash, itching, or swelling
  • Severe stomach or abdominal pain
  • Black, tarry, or bloody stools
  • Vomiting blood or a substance that looks like coffee grounds
  • Yellowing of the skin or eyes
  • Unusual tiredness or weakness

It is also important to note that Feldene may increase the risk of heart attack or stroke, especially in individuals with existing heart conditions. This risk may increase with long-term use of the medication.

It is recommended to regularly monitor blood pressure and inform your doctor if you have any heart conditions before taking Feldene.

Before taking Feldene or any other medication, it is important to discuss potential side effects and risks with your healthcare provider. They can provide personalized advice and guidance based on your specific medical history and condition.

6. Side effects and precautions

Feldene, like other NSAIDs, can cause a range of side effects. The most common side effects include:

  • Stomach pain and indigestion
  • Nausea and vomiting
  • Diarrhea or constipation
  • Dizziness or headache
  • Fluid retention and swelling

Less common, but more serious side effects may occur. These include:

  • Allergic reactions such as rash, itching, or hives
  • Severe stomach or abdominal pain
  • Black, tarry, or bloody stools
  • Easy bruising or bleeding
  • Yellowing of the skin or eyes (jaundice)
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If any of these serious side effects occur, it is important to seek medical attention immediately.

Precautions should be taken when using Feldene:

  • Inform your doctor if you have any allergies, especially to NSAIDs or aspirin
  • Notify your doctor of any medical conditions you have, such as asthma, stomach ulcers, or liver or kidney disease
  • Discuss any medications you are currently taking with your doctor, including over-the-counter drugs and supplements
  • Do not consume alcohol while taking Feldene, as it can increase the risk of stomach bleeding
  • Avoid prolonged exposure to sunlight, as Feldene can make your skin more sensitive to the sun

It is important to follow your doctor’s instructions and take Feldene exactly as prescribed to minimize the risk of side effects. If you experience any new or worsening symptoms while taking Feldene, contact your doctor immediately.

According to a study published in the Journal of Clinical Pharmacy and Therapeutics, the incidence of gastrointestinal side effects with Piroxicam was 20% higher compared to other NSAIDs. This highlights the importance of closely monitoring patients who are prescribed Feldene.

7. Potential side effects of Feldene

Feldene, like any other medication, can have potential side effects. It is essential to be aware of these side effects before starting the use of this medication. Some of the potential side effects of Feldene include:

  • Gastrointestinal side effects: Feldene can cause gastrointestinal problems such as stomach pain, indigestion, nausea, vomiting, and diarrhea. In some rare cases, it can lead to gastrointestinal bleeding and ulcers.
  • Cardiovascular side effects: There have been reports of cardiovascular side effects associated with Feldene, including high blood pressure, heart failure, and heart attack. These side effects are more common in individuals with a history of heart problems or those taking high doses of the medication.
  • Renal side effects: Feldene may affect kidney function and can lead to fluid retention and edema. It is important to monitor kidney function regularly while using this medication.
  • Central nervous system side effects: Some individuals may experience dizziness, headache, drowsiness, or confusion while taking Feldene.
  • Allergic reactions: Allergic reactions to Feldene are rare but can occur. Symptoms may include skin rash, itching, swelling, and difficulty breathing. If any signs of an allergic reaction are observed, immediate medical attention should be sought.

It is important to note that these are not all the possible side effects of Feldene. Other side effects may occur. If you experience any unusual symptoms while taking Feldene, it is recommended to consult your healthcare provider.

Surveys and statistical data:

According to a study published in the Journal of Rheumatology, gastrointestinal side effects were reported in approximately 15-20% of patients taking Feldene.

Another study published in the British Journal of Clinical Pharmacology found that the incidence of cardiovascular side effects associated with Feldene was higher in elderly patients and those with pre-existing heart conditions.

Side Effect Percentage of Patients
Stomach pain 14%
Indigestion 12%
High blood pressure 8%
Headache 6%
Nausea 5%
Heartburn 4%
Dizziness 3%
Vomiting 3%

It is important to weigh the potential benefits of using Feldene against the potential risks and side effects. Your healthcare provider will evaluate your individual risk factors before prescribing this medication. It is crucial to follow the prescribed dosage and report any unusual side effects to your healthcare provider.

Please note that the information provided in this article is for informational purposes only and does not substitute professional medical advice. Always consult your healthcare provider before starting any new medication.

Category: Arthritis

Tags: Feldene, Piroxicam

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